Citation Information :
Shah DN, Patel JC, Puttanikar NY, Shah DS, Managutti SA. Evaluation of Clinical Efficacy of Cissus quadrangularis in Pain Management and Bone Healing after Implant Placement: A Pilot Study. Int J Oral Implantol Clin Res 2015; 6 (2):35-39.
Background: The ancient ayurveda science of medicine describes various herbal preparations that achieve the hastening of bone healing and relieve from pain and swelling.
Aim: To evaluate the clinical efficacy of Cissus quadrangularis in pain management and bone healing after implant placement.
Objective: To evaluate the clinical and biochemical parameters using C. quadrangularis after implant placement in terms measurements of pain, swelling and serum alkaline phosphatase level.
Type of study: Prospective randomized control study
Materials and methods: The patients were divided in two groups—study group and control group. Three patients in each group received implants either single implants or multiple implants. Study group was given C. quadrangularis without any additional medicine and control group was given routine antibiotics (amoxicillin 500 mg and diclofenac sodium). Pain was assessed using visual analog scale (VAS) at 3rd, 5th days and, after 1 week, swelling was checked in form of mild, moderate and severe. And, serum alkaline phosphatase was recorded preoperatively and 4th and 8th weeks of postoperative to evaluate bone healing.
Results: Pain and swelling are minimal, and bone healing is maximum in study and in control groups. There was an increase in serum alkaline phosphatase level at different follow-up in study groups compare to control group.
Conclusion: Use of C. quadrangularis after implant placement showed significant effect on pain and swelling management. Also rising level of serum alkaline phosphatase indicates new bone formation thus helps in osteointegration.
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