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VOLUME 5 , ISSUE 3 ( September-December, 2014 ) > List of Articles

RESEARCH ARTICLE

A Comparative Study to Assess the Quality of Bone following Ridge Augmentation with Autografts and Allografts: A Prospective Study

Arjun Krishnadas, Ramkumar Subramanian, G Giri

Citation Information : Krishnadas A, Subramanian R, Giri G. A Comparative Study to Assess the Quality of Bone following Ridge Augmentation with Autografts and Allografts: A Prospective Study. Int J Oral Implantol Clin Res 2014; 5 (3):88-91.

DOI: 10.5005/jp-journals-10012-1122

License: CC BY-ND 4.0

Published Online: 00-12-2014

Copyright Statement:  Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim: The aim of this study was to investigate the quality of bone at the augmented site in the anterior maxilla and mandible. Materials and methods: Ten patients with inadequate bone for implant placement were included in this study. Of these 10 patients with inadequate bone volume, five were chosen to be treated with autogenous bone grafts (AT) and rest five patients were treated with freeze dried corticocancellous allografts (AL). Three months following grafting, biopsies of the grafted area were obtained using a 3 mm trephine bur and were histologically evaluated. Results: Histological analysis revealed areas of new bone formation with thick trabeculae with lacunae containing osteocytes in the autogenous group, whereas the allograft group showed segments of necrotic bone with empty lacunae. Although, the AL group has an inherent advantage of avoidance of a secondary surgical site, showed decreased bone remodeling as compared to the autografts. Conclusion: All the 10 patients underwent implant placement. The reports regarding the nature of bone obtained during implant placement clearly depicts a comparable histological variation at the grafted site.


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  1. Chiapasco M, et al. Augmentation procedures for the rehabilitation of deficient edentulous ridges with oral implants. Clin Oral Implant Res 2006;17(S2):136-159.
  2. Windmark G, et al. Mandibular bone graft in the anterior maxilla for single-tooth implants. Int J Oral Maxillofac Surg 1997;26(2): 106-109.
  3. Hof M, et al. Esthetic evaluation of single-tooth implants in the anterior maxilla following autologous bone augmentation. Clin Oral Implants Res 2013 Aug;24(A100):88-93.
  4. David R Jr, et al. Principles of bone grafting. Oral Maxillo fac Surg Clin of North America 2010;22(3):295-300.
  5. Philips JH, et al. Fixation effects on membranous and endochondral onlay bone graft revascularization and bone deposition. Plastic Reconst Surg 1990;85(6):891-897.
  6. Hardesty, et al. Craniofacial onlay bone grafting: a prospective evaluation of graft morphology, orientation and embryonic origin. Plastic Reconst Surg 1990;85(1):5-14.
  7. Zerbo IR, et al. Fate of monocortical bone blocks grafted in the human maxilla: a histological and histomorphometric study. Clin Oral Implant Res 2003;14(6):759-766.
  8. Cordaro L, et al. Mandibular bone harvesting for alveolar reconstruction and implant placement subjective and objective crosssectional evaluation of donor and recipient site up to 4 years. Clin Oral Implant Res 2011;22(11):1320-1326.
  9. Sbordone L, et al. Clinical survey of neurosensory side-effects of mandibular parasymphyseal bone harvesting. Int J Oral Maxillofac Surg 2009;38(2):139-145.
  10. Cawood JJ, et al. A classification of the edentulous jaws. Int J Oral Maxillofac Surg 1988;17(4):232-236.
  11. Meijndert L, et al. Bone quality at the implant site after reconstruction of a local defect of the maxillary anterior ridge with chin bone or deproteinised cancellous bovine bone. Int J Oral Maxillofac Surg 2005;34(8):877-884.
  12. Acocella A, et al. Clinical, histological and histo morphometric evaluation of the healing of mandibular ramus bone block grafts for alveolar ridge augmentation before implant placement. J Craniomaxillofac Surg 2010;38(3):222-230.
  13. Simpson D, et al. Viable cells survive in fresh frozen human bone allografts. Acta Orthopedics 2007;78(1):26-30.
  14. Wingfield C, et al. Cryopreservation of osteochondral allografts: dimethyl sulfoxide promotes angiogenesis and immune tolerance in mice. J Bone Joint Sur g Am 2002;84(8):1420-1429.
  15. Aho AJ, et al. Immune responses and clinical outcomes of massive human osteoarticular allografts. Clin Orthoped Relat Res 1998;346:196-206.
  16. Schwedhelm ER, Raigrodski AJ. A technique for locating implant abutment screws of posterior cement-retained metalceramic restorations with ceramic occlusal surfaces. J Prosthet Dent 2006;95:165-167.
  17. Clausen GF. The lingual locking screw for implant-retained restorations—aesthetics and retrievability. Aust Prosthodont J 1995;9:17-20.
  18. Okamoto M, Minagi S. Technique for removing a cemented super struc ture from an implant abutment. J Prosthet Dent 2002;87:241-242.
  19. Doerr J. Simplified technique for retrieving cemented implant restorations. J Prosthet Dent 2002;88:352-353.
  20. Studer S, Naef R, Schärer P. Adjustment of localized alveolar ridge defects by soft tissue transplantation to improve mucogingival esthetics: a proposal for clinical classification and an evaluation of procedures. Quintessence Int 1997;28:785-805.
  21. Seibert J, Lindhe J. Esthetics in periodontal therapy. In: Lindhe J, Karring T, Lang N, editors. Clinical Periodontology and Implant Dentistry. 3rd ed. Copenhagen: Munksgaard, 1997:647-681.
  22. Scharf D, Tarnow D. Modified roll technique for localized alveolar ridge augmentation. Int J Periodontics Restorative Dent 1992;12:415-425.
  23. Kan JY, Rungcharassaeng K, Umezu K, Kois JC. Dimensions of peri-implant mucosa: an evaluation of maxillary anterior single implants in humans. J Periodontol 2003;74:557-562.
  24. Spear FM. Maintenance of the interdental papilla following anterior tooth removal. Pract Periodontics Aesthet Dent 1999; 11:21-28.
  25. Park SH, Wang HL. Pouch roll technique for implant soft tissue augmentation: a variation of the modified roll techni que. Int J Periodontics Restorative Dent 2012;32:e116-e121.
  26. Kim CS. Long-term results from soft and hard tissue augmentation by a modified vascularized interpositional periostealconnective tissue technique in the maxillary anterior region. J Oral and Maxillofac Surg 2012;70:484-491.
  27. Neyt L, De Clercq C, Abeloos J, Mommaerts M. Mandibular fractures following insertion of denial implants. Acta Stomatol Belg 1993;90:251-258.
  28. Kan JY, Lozada JL, Boyne PJ, Goodacre CJ, Rungcharassaeng K. Mandibular fracture after endosseous implant placement in conjunction with inferior alveolar nerve transposition: a patient treatment report. Int J Oral Maxillofac Implants 1997;12: 655-659.
  29. Raghoebar GM, Stellingsma K, Batenburg RH, Vissink A. Etiology and management of mandibular fractures associated with endosteal implants in the atrophic mandible. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89:553-559.
  30. Laboda G. Life-threatening hemorrhage after placement of an endosseous implant: report of case. J Am Dent Assoc 1990;121: 599-600.
  31. Mason ME, Triplett RG, Alfonso WF. Life-threatening hemorrhage from placement of a dental implant. J Oral Maxillofac Surg 1990;48:201-244.
  32. Ten Bruggenkate CM, Krekeler G, Kraaijenhagen HA, Foitzik C, Oosterbeek HS. Hemorrhage of the floor of the mouth resulting from lingual perforation during implant placement: a clinical report. Int J Oral Maxillofac Implants 1993;8:329-334.
  33. Mordenfeld A, Andersson L, Bergstrom B. Hemorrhage in the floor of the mouth during implant placement in the edentulous mandible: a case report. Int J Oral Maxillofac Implants 1997; 12:558-561.
  34. Givol N, Chaushu G, Halamish-Shani T, Taicher S. Emergency tracheostomy following life-threatening hemorrhage in the floor of the mouth during immediate implant placement in the mandibular canine region. J Periodontol 2000;71: 1893-1895.
  35. Dwyer MS. Re: Near fatal venous nitrogen/air embolism occurrence while inserting cylindrical endosseous oral implants. J Periodontol 1992;63(1):63.
  36. Theisen FC, Shultz RE, Elledge DA. Displacement of a root form implant into the mandibular canal. Oral Surg Oral Med Oral Pathol 1990;70:24-28.
  37. Bergermann M, Donald PJ, Wengen DF. Screwdriver aspiration: a complication of dental implant placement. Int J Oral Maxillofac Surg 1992;21:339-341.
  38. Li KK, Varvares MA, Meara JG. Descending necrotizing mediastinitis: acomplication of dental implant surgery. Head Neck 1996;18:192-196.
  39. Krepler K, Wedrich A, Schranz R. Intraocular hemorrhage associated with dental implant surgery. Am J Ophthal 1996; 122:745-746.
  40. Strull GE, Dym H. Singultus: a distressing postsurgical complication. J Oral Maxillofac Surg 1995;53:711-713.
  41. Goodacre CJ, Benal G. Clinical complications with implants and implant prostheses. J Prosthet Dent 2003;90:121-132.
  42. Adell R, Lekholm U, Rockler B, Branemark PI. A 15-year study of osseointegrated implants in the treatment of the edentulous jaw. Int J Oral Surg 1981;10:387-416.
  43. Jemt T. Failures and complications in 391 consecutively inserted fixed prostheses supported by Branemark implants in edentulous jaws: a study of treatment from the time of prosthesis placement to the first annual check-up. Int J Oral Maxillofac Implants 1991;6:270-276.
  44. Misch CE. Contemporary Implant Dentistry. 3rd ed. St. Louis: CV Mosby; 2008 Feb 4. p. 1120.
  45. Implant text risk factors in implant dentistry: simplified clinical analysis for predictable treatment. 2nd ed. Franck Renouard, DDS.
  46. Implant Dentistry—The Most Promising Discipline of Dentistry. Implant Complications Ma Angeles Sánchez Garcés, Jaume Escoda-Francolí and Cosme Gay-Escoda University of Barcelona, Faculty of Dentistry, Spain.
  47. Mendonca G, Mendonca DB, Fernandes Neto AJ, Neves FD. Use of distraction osteogenesis for repositioning of an osseointegrated implant: a case report. Int J Oral Maxillofac Implants 2008;23(3):551-555.
  48. Georgiev T, Nogalchev K. Local complications occuring during dental implantation. J Int Med Assoc Bulgaria 2010;16(4):35-37.
  49. Elie E. Daou Stud attachments for the mandibular implant retained overdentures: Prosthetic complications. A literature review. Remov able Prosthodontics Department, School of Dentistry, Lebanese University, Beirut, Lebanon The Saudi Dental Journal (2013). Available at: http://dx.doi.org/10.1016/j. sdentj.2012.12.003
  50. Steigmann M. Aesthetic flap design for correction of buccal fenestration defects, practical procedures and aesthetic dentistry: PPAD 2008;20(8):487-493.
  51. Chrcanovic BR, Custodio AL. Mandibular fractures associated with endo steal implants, oral and maxillofacial surgery 2009;13 (4):231-238.
  52. Misch CE, Resnik R. Mandibular nerve neurosensory impairment after dental implant surgery: management and protocol. Implant Dentistry 2010;19(5):378-386.
  53. Wittneben JG, Millen C, Bragger U. Clinical performance of screw-versus cement-retained fixed implant-supported reconstructions—a systematic review. Int J Oral Maxillofac Implants 2014;29(Suppl):84-98.
  54. Moghadam HG, Cols Y, Histomorphometric evaluation of bone regeneration using allogenic and alloplastic bone substitutes. J Oral Maxillofac Surg 2004 Feb;62(2):202-13.
  55. Revie Leziy SS, Miller BA. Guided implant surgery and the use of osteotomes for rehabilitation of the maxilla. Pract Proced Aesthet Dent 2006 Jun;18(5):293-95.
  56. Pereira CC, Gealh WC, Nogueira LM, Garcia IR JR, Okamoto R. Piezosurgey applied to implant dentistry: Clinical and biological aspects. J Oral Implantol 2012 Jan 4[Epub ahead of print].
  57. Viña-Almunia J, Maestre-Ferrín L, Alegre-Domingo T, Peñarrocha-Diago MA. Survival of implants placed with the osteotome technique: An update. Med Oral Patol Oral Cir Bucal 2012;17(5):e765-68.
  58. Piano S. A simple way to plan implant positioning: the ‘Stechnique’. Eur J Esthet Dent Autumn; 2011;6(3):328-41.
  59. Kfir E, Goldestein M, Abramovitz I, Mazor Z, Kfir V, Kaluski E. The effects of sinus membrane pathology on bone augmentation and procedural outcome using minimal invasive antral membrane balloon elevation. J Oral Implantol 2012 Mar
  60. [Epub ahead of print].
  61. Kaneko T, Masuda I, Horie N, Shimoyama T. New bone formation in nongrafted sinus lifting with space-maintaining management: A novel technique using a titanium bone fixation device. J Oral Maxillofac Surg 2012Mar;70(3):e217-24.
  62. Crespi R, Capparè P, Gherlone E. Osteotome sinus floor elevation and simultaneous implant placement in grafted biomaterial sockets: 3 years of follow-up. J Periodontol 2010 Mar;81(3):344-49.
  63. Brägger U, Gerber C, Joss A, Haenni S, Meier A, Hashorva E, Lang NP. Patterns of tissue remodeling after placement of ITI dental implants using an osteotome technique: A longitudinal radiographic case cohort study. Clin Oral Implants Res 2004 Apr;15(2):158-66.
  64. Lindgren C, Mordenfeld A, Hallman M. A prospective 1-year clinical and radiographic study of implants placed after maxillary sinus floor augmentation with synthetic biphasic calcium phosphate or deproteinized bovine bone. Clin Implant Dent Relat Res 2012 Mar;14(1):41-50.
  65. Guyot M, Dubuc O, Richard NP, Dutour O. Comparison between direct clinical and digital photogrammetric measurements in patients with 22q11 microdeletion. Int J Oral Maxillofac Surg 2003 June;32(3):246-52.
  66. Jemt LT. Photogrammetric measurements of implant positions. Description of a technique to determine the fit between implants and superstructures. Clin Oral Implants Res 2003;5(1):30-36.
  67. Summers RB. The osteotome technique: Part 3. Less invasive methods of elevating the sinus floor. Compendium 1994;15: 702-04.
  68. Taschieri S, Corbella S, Saita M, Tsesis I, Del Fabbro M. Osteotome-mediated sinus lift without grafting material: A review of literature and a technique proposal. Hindawi Publishing Corporation. Int J Dent 2012, Article ID 849093, 9 pages.
  69. Taschieri S, Corbella S, Del Fabbro M. Use of plasma rich in growth factor for Schneiderian membrane management during maxillary sinus augmentation procedure. J Oral Implantol 2012;38(5):621-27.
  70. Mol A, Van de Stel APF. Application of digital image analysis in dental radiography for the description of periapical bone lesions: A preliminary study. (Special tissue in dentistry) Trans Biomed Eng 1991;38:357-59.
  71. Palioto DB. Sato S. Computer assisted image analysis methods for evaluation of periodontal wound healing. Braz Dent J 2001;12(3):167-72.
  72. Ganz SD. Cone beam computed tomography-assisted treatment planning concepts. Dent Clin North Am 2011 Jul;55(3):515-36.
  73. Peck JN, Conte GJ. Radiologic techniques using CBCT and 3-D treatment planning for implant placement. J Calif Dent Assoc 2008 Apr;36(4):287-90.
  74. Fienitz T, Schwarz F, Ritter L, Dreiseidler T, Becker J, Rothamel D. Accuracy of cone beam computed tomography in assessing peri-implant bone defect regeneration: A histologically controlled study in dogs. Clin Oral Implants Res 2012Jul;23(7):882-87.
  75. Leziy SS, Miller BA. Guided implant surgery and the use of osteotomes for rehabilitation of the maxilla. Pract Proced Aesthet Dent 2006 Jun;18(5):293-95.
  76. Beretta M, Cicciù M, Bramanti E, Maiorana C. Schneider membrane elevation in presence of sinus septa: Anatomic features and surgical management. Hindawi Publishing Corporation. Int J Dent 2012;Article ID 261905, 6 pages.
  77. Ganz SD. Computer-aided design/computer-aided manufacturing applications using CT and cone beam CT scanning technology. Dent Clin North Am 2008 Oct;52(4):777-808.
  78. Chung S, McCullagh A, Irinakis T. Immediate loading in the maxillary arch: Evidence-based guidelines to improve success rates: A review. J Oral Implantol 2011 Oct; 37(5):610-17.
  79. Bertassoni LE, Marshall GW. Papain-gel degrades intact nonmineralized type I collagen fibrils. Scanning 2009 Nov- Dec;31(6):253-258.
  80. Moon SE, Kim HY, Cha JD. Synergistic effect between clove oil and its major compounds and antibiotics against oral bacteria. Arch Oral Biol 2011 Sep;56(9):907-916.
  81. Pinto E, Vale-Silva L, Cavaleiro C, Salgueiro L. Antifungal activity of the clove essential oil from Syzygium aromaticumon, candida, aspergillus and dermatophyte species. J Med Microbiol 2009 Nov;58(Pt 11):1454-1462.
  82. Olajide OA, Makinde JM, Awe SO. Evaluation of the pharmacological properties of nutmeg oil in rats and mice. Pharma Biol 2000;38(5):385-390.
  83. Thanoon SZ, Al-Refai AS, Kamal A. Antibacterial effect and healing potential of nutmeg oil for chemically induced oral ulcerations in rabbits. Zanco J Med Sci 2013;17(2): 393-399.
  84. Mitwally MF, Casper RF. Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate. Fertil Steril 2001;75:305-09.
  85. Sammour A, Bijan MM, Tan SL, Tulandi T. Prospective randomised trial comparing the effects of letrazole (LE) and clomiphene citrate (CC) on follicular development, endometrial thickness and pregnancy rate in patients undergoing superovulation prior to intrauterine insemination (IUI). Fertil Steril 2001;76(Suppl 1):S110.
  86. Mitwally MF, Casper RF. Single-dose administration of an aromatase inhibitor for ovarian stimulation. Fertil Steril 2005;83:229-31.
  87. Fisher SA, Reid RL, Van Vugt DA, Casper RF. A randomized double-blind comparison of the effects of clomiphene citrate and the aromatase inhibitor letrozole on ovulatory function in normal women. Fertil Steril 2002;78:280-85.
  88. Fatemi HM, Kalibianakis E, Tournaye H, Camus M, Van Steirteghem AC, Devroey P. Clomiphene citrate vs letrozole for ovarian stimulation: A pilot study. Reprod Biomed Online 2003;7:543-46.
  89. Hu Y, Cortvrindt R, Smitz J. Effects of aromatase inhibition on in vitro follicle and oocyte development analyzed by early preantral mouse follicle culture. Mol Reprod Dev 2002;61: 549-59.
  90. Shetty G, Krishnamurthy H, Krishnamurthy HN, Bhatnagar S, Moudgal NR. Effect of estrogen deprivation on the reproductive physiology of male and female primates. J Steroid Biochem Mol Biol 1997;61:157-66.
  91. Mitwally MF, Casper RF. Aromatase inhibition reduces gonadotrophin dose required for controlled ovarian stimulation in women with unexplained infertility. Hum Reprod 2003;18:1588-97.
  92. Mitwally MF, Casper RF. Aromatase inhibition improves ovarian response to follicle-stimulating hormone in poor responders. Fertil Steril 2002;77:776-80.
  93. Goswami SK, Das T, Chattopadhyay R, Sawhney V, Kumar J, Chaudhury K, Chakravarty BN, Kabir SN. A randomized single blind controlled trial of letrozole as a low-cost IVF protocol in women with poor ovarian response: A preliminary report. Hum Reprod 2004;19:2031-35.
  94. Newkirk KM, Chandler HL, Parent AE, et al. Ultraviolet radiation-induced corneal degeneration in 129 mice. Toxicol Pathol 2007;35:819-26.
  95. Pettenati MJ, Sweatt AJ, Lantz P, et al. The human cornea has a high incidence of acquired chromosome abnormalities. Hum Genet 1997;101:26-29.
  96. Snibson GR. Collagen cross-linking: A new treatment paradigm in corneal disease—a review. Clin Experiment Ophthalmol 2010;38:141-53.
  97. Spoerl E, Raiskup-Wolf F, Kuhlisch E, Pillunat LE. Cigarette smoking is negatively associated with keratoconus. J Refract Surg 2008;24:S737-40.
  98. Rabinowitz YS, Nesburn AB, McDonnell PJ. Videokeratography of the fellow eye in unilateral keratoconus. Ophthalmology 1993;100:181-86.
  99. Goodrich DW, Lee WH. The molecular genetics of retinoblastoma. Cancer Surv 1990;9:529-54.
  100. Moodaley LC, Woodward EG, Liu CS, Buckley RJ. Life expectancy in keratoconus. Br J Ophthalmol 1992;76:590-91.
  101. Honein MA, Dawson AL, Petersen EE, Jones AM, Lee EH, Yazdy MM, Ahmad N, Macdonald J, Evert N, Bingham A, et al. Birth defects among fetuses and infants of US women with evidence of possible Zika virus infection during pregnancy. JAMA 2017 Jan 3;317(1):59-68.
  102. Chervenak FA, Jeanty P, Cantraine F, Chitkara U, Venus I, Berkowitz RL, Hobbins JC. The diagnosis of fetal microcephaly. Am J Obstet Gynecol 1984 Jul 1;149(5):512-517.
  103. Papageorghiou AT, Thilaganathan B, Bilardo CM, Ngu A, Malinger G, Herrera M, Salomon LJ, Riley LE, Copel JA. ISUOG Interim Guidance on ultrasound for Zika virus infection in pregnancy: information for healthcare professionals. Ultrasound Obstet Gynecol 2016 Apr;47(4):530-532.
  104. Chibueze EC, Parsons AJ, Lopes KD, Yo T, Swa T, Nagata C, Horita N, Morisaki N, Balogun OO, Dagvadorj A, et al. Diagnostic accuracy of ultrasound scanning for prenatal microcephaly in the context of Zika virus infection: a systematic review and meta-analysis. Sci Rep 2017 May 23;7(1):2310.
  105. Cordeiro MT. Zika virus: laboratory diagnosis. In: Zika in focus. Springer International Publishing; 2017. pp. 59-62.
  106. Mlakar J, Korva M, Tul N, Popović M, Poljšak-Prijatelj M, Mraz J, Kolenc M, Resman Rus K, Vesnaver Vipotnik T, Fabjan Vodušek V, et al. Zika virus associated with microcephaly. N Engl J Med 2016 Mar 10;374(10):951-958.
  107. Zare Mehrjardi M, Keshavarz E, Poretti A, Hazin AN. Neuroimaging findings of Zika virus infection: a review article. Jpn J Radiol 2016 Dec;34(12):765-770.
  108. Oliveira Melo AS, Malinger G, Ximenes R, Szejnfeld PO, Alves Sampaio S, Bispo de Filippis AM. Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg? Ultrasound Obstet Gynecol 2016 Jan;47(1):6-7.
  109. Araujo AQ, Silva MT, Araujo AP. Zika virus-associated neurological disorders: a review. Brain 2016;139(8):2122-2130.
  110. Brasil P, Pereira JP Jr, Moreira ME, Ribeiro Nogueira RM, Damasceno L, Wakimoto M, Rabello RS, Valderramos SG, Halai UA, Salles TS, et al. Zika virus infection in pregnant women in Rio de Janeiro. N Engl J Med 2016 Dec 15;375(24):2321-2334.
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