International Journal of Oral Implantology & Clinical Research

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VOLUME 5 , ISSUE 1 ( January-April, 2014 ) > List of Articles

ORIGINAL RESEARCH

Titanium Hypersensitivity: A Clinical Study

CL Satish Babu, Mohammed Fayaz Pasha, Soumyadev Satpathy, Giriyanna Gowda

Citation Information : Babu CS, Pasha MF, Satpathy S, Gowda G. Titanium Hypersensitivity: A Clinical Study. Int J Oral Implantol Clin Res 2014; 5 (1):8-11.

DOI: 10.5005/JP-Journals-10012-1108

License: CC BY-ND 4.0

Published Online: 01-04-2014

Copyright Statement:  Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Titanium implants are extensively used to replace the missing natural teeth in prosthodontics. However, allergic reactions to titanium in dentistry has not received its due attention. Literature reports sensitivity to titanium ranging from 0.6 to 5% of the general population. The allergic reactions in patients who are sensitive to titanium ranges from type I to IV with symptoms ranging from vague pain, skin rashes to implant failure. The aim of this study was to evaluate the presence of titanium allergy by anamnesis and examination of subjects using titanium dioxide 0.5% in patch test methodology. A sample size of four hundred healthy subjects with no previous history of immunosuppression were included. Titanium dioxide 0.5% concentration in petrolatum was used to conduct the patch test. A history of allergy to any other allergen was recorded as a part of the study. Under the limitations of this study, it was concluded that, titanium can induce hypersensitivity response in susceptible patients. From this study it was observed that the hypersensitivity reactions to titanium was 0.3% in all the subjects tested. It was also observed that the individuals with a prior history of allergy to other known allergens were more susceptible to allergic reactions to titanium. Limitations of the study was the absence of a wider age group of population for this study. Future research is recommended by considering a wider age group of population and a longterm followup of patients.


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